i have the canon 5d & 5dII with attached 70-200 is f2.8 + 85 f1.2 + 135 f2 +50 ziess flash and some other accessories and it fits comfortably on my back with no issues of-course the only down fall is that i have to remove the bag to change lenses but if you traveling far and need to put everything in one place this is the one for you
Lowepro Fastpack 350 Black